Fliban 100 mg (which contains Flibanserin, a drug used primarily for treating hypoactive sexual desire disorder in women) with grapefruit or grapefruit juice can lead to significant interactions. Why? Grapefruit contains compounds called furanocoumarins that inhibit an enzyme called CYP3A4 in the liver and intestines. Flibanserin is metabolized primarily by CYP3A4. When grapefruit inhibits this enzyme, it slows down the metabolism of Flibanserin, causing higher blood levels of the drug than intended. Potential consequences of taking Fliban 100 mg  with grapefruit: Increased risk of serious side effects such as: Severe low blood pressure (hypotension) Fainting (syncope) Dizziness Other related cardiovascular issues Recommendation: Avoid consuming grapefruit or grapefruit juice while taking Flibanserin (Fliban 100 mg). Always check with your healthcare provider or pharmacist about possible food and drug interactions before starting new medications. If you have taken Flibanserin with grapefruit and experience symptoms like dizziness, fainting, or severe headache, seek medical attention promptly.