Tadalista 10 mg) can have some effect on heart-related functions, but it usually does not directly increase or dangerously change heart rate in most healthy people. What it actually does Tadalafil mainly: Relaxes blood vessels (vasodilation) Lowers blood pressure slightly in some users Improves blood flow to the penis during sexual stimulation Because of these blood vessel effects, the heart may sometimes respond indirectly. Possible effects on heart rate In some people, especially sensitive individuals, it may cause: Mild increase in heart rate (reflex response to slightly lower blood pressure) Palpitations (feeling of heartbeat awareness) Light dizziness during standing or exertion However, these effects are usually mild and temporary. When it can be risky Tadalista 10 mg should be used carefully or avoided if you have: Serious heart disease or recent heart attack/stroke Low blood pressure Use of nitrate medicines (like nitroglycerin) → can cause dangerous BP drop Severe rhythm disorders (without medical supervision) During sexual activity Keep in mind: Sexual activity itself increases heart rate and cardiac workload more than the medicine does The combination of exertion + tadalafil is what matters in people with heart conditions Simple summary Tadalista 10 mg does not usually directly raise heart rate significantly, but it can indirectly cause mild changes due to blood pressure effects in some individuals. If you want, I can also tell you which ED medicines are considered safest for people with mild heart conditions.