Poxet 90 mg contains dapoxetine, a short‑acting selective serotonin reuptake inhibitor (SSRI) used on‑demand to treat premature ejaculation (PE) in men. It’s not intended for continuous long‑term daily use like antidepressants or other chronic medications. Here’s what you should know about long‑term use and safety:   How It’s Intended to Be Used Dapoxetine (Poxet 90 mg) is designed to be taken only when needed, typically 1–3 hours before sexual activity, not every day. Do not take more than one dose in 24 hours.   Long‑Term Daily Use: Not Recommended Poxet and other dapoxetine pills are not created for chronic daily Poxet 90 mg like many SSRIs for depression. There is limited clinical evidence on the long‑term safety of using dapoxetine every day for months or years, because most research and guidelines treat it as occasional, on‑demand therapy. Some advisory guidelines explicitly note that long‑term safety outcomes are not established and caution about prolonged use.  Potential Risks with Frequent/Daily Use Even though dapoxetine has a short half‑life and is eliminated fairly quickly from the body, using it frequently could increase your risk of side effects typical of SSRIs or aggravate some conditions: Common short‑term side effects (even with occasional use): Headache, dizziness, nausea Insomnia or sleep disturbances Dry mouth Fatigue or drowsiness These usually are mild and fleeting when taken as directed. Concerns if used often: Mood changes (since it affects serotonin, a brain neurotransmitter) Dizziness or fainting due to blood pressure changes Unpredictable effects on sleep and cognitive function Potential interactions with other drugs affecting serotonin (risk of serotonin syndrome) Because dapoxetine is an SSRI, PS‑like (post‑SSRI sexual dysfunction) concerns or long‑term mood effects are a theoretical possibility if misused, though solid clinical data on this specific medication and frequent use is lacking and incomplete.