Filitra 10, which contains vardenafil, is a phosphodiesterase type 5 (PDE5) inhibitor prescribed for erectile dysfunction. While Filitra 10 mg can be effective, certain health conditions make its use unsafe. It is contraindicated in patients with severe cardiovascular disorders, such as recent heart attack, stroke, uncontrolled arrhythmias, or severe heart failure, because sexual activity may worsen these conditions. Men with severe liver impairment or end-stage kidney disease requiring dialysis should avoid Filitra 10. It is also unsafe in those with low blood pressure or uncontrolled high blood pressure. Individuals taking nitrates or nitric oxide donors for chest pain must not use it due to the risk of life-threatening hypotension. Caution is also required in patients with retinitis pigmentosa, anatomical penile deformities, or a history of priapism. Consulting a healthcare provider before use ensures safety and proper guidance.