Tadarise 40 mg may affect ejaculation indirectly, but its main purpose is to treat erectile dysfunction, not premature ejaculation. Tadarise usually contains tadalafil, which improves blood flow to the penis. How it may affect ejaculation Erection: Helps you achieve and maintain an erection. Tadarise 40 mg timing: Usually does not directly delay ejaculation or reliably increase the time before climax. Erection after ejaculation: May help you achieve another erection sooner when you are sexually aroused, although it does not guarantee a shorter recovery period. Orgasm: Usually does not directly change orgasm intensity or sensation. Is 40 mg safe? For erectile dysfunction, the usual maximum recommended on-demand tadalafil dose is 20 mg in 24 hours. A 40 mg dose is higher than recommended for this purpose and may increase the risk of headache, dizziness, low blood pressure, and other adverse effects. Do not take another dose until you've checked the dose with a clinician.