Tazzle 10 mg (tadalafil) can affect blood pressure because tadalafil relaxes blood vessels. It can cause a small drop in blood pressure, which is usually tolerated by healthy people. You may experience dizziness, light-headedness, flushing, or fainting, especially when standing up quickly. Tazzle 10 mg effect can be stronger if you take blood-pressure medicines, alpha-blockers, or drink a lot of alcohol. Do not take tadalafil with nitrate medicines such as nitroglycerin or isosorbide. The combination can cause a dangerous fall in blood pressure. If you have very low blood pressure, uncontrolled high blood pressure, or significant heart disease, discuss tadalafil with a doctor before taking it. If you tell me your usual blood-pressure reading and any BP medicines you're taking, I can explain how Tazzle 10 mg might affect you.