When taking Poxet 90 mg, especially if you have other health conditions, it is important to follow the guidance of a healthcare provider to minimize potential risks and side effects. Poxet 90 mg contains Dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI) commonly used to treat premature ejaculation (PE). Here are some general guidelines and considerations for taking Poxet 90 mg if you have underlying health conditions: General Guidelines for Taking Poxet 90 Mg: Recommended Dose: The usual recommended dose is one tablet of Poxet 90 mg taken 1 to 3 hours before sexual activity. Do not take more than one tablet per day. Administration: Take the tablet with a full glass of water. It can be taken with or without food, but for best results, it is often recommended to take it on an empty stomach or after a light meal. Do not take daily: Poxet 90 mg is intended to be used on an as-needed basis and should not be taken daily. Considerations for Specific Health Conditions: 1. Heart Conditions (e.g., heart disease, arrhythmia) Caution: Dapoxetine can affect the cardiovascular system by potentially increasing heart rate and blood pressure. If you have a heart condition, such as arrhythmia (irregular heartbeats), heart disease, or a history of heart attack, you should consult your doctor before using Poxet 90 mg. Potential Interactions: Dapoxetine may interact with medications used to treat heart conditions, including certain anti-arrhythmic drugs and beta-blockers. It is essential to check for any potential drug interactions. 2. Liver or Kidney Issues Liver Impairment: If you have liver disease or liver dysfunction, your doctor may recommend a lower dose or alternative treatment. Poxet 90 mg should be used with caution in individuals with liver impairment, as the medication is metabolized by the liver. Kidney Impairment: For individuals with kidney problems, Poxet 90 mg should also be used with caution, and your doctor may adjust the dosage accordingly. 3. Mental Health Conditions (e.g., Depression, Anxiety) Depression and Anxiety: Since Dapoxetine is a type of SSRI, it can affect serotonin levels in the brain. If you have depression, anxiety, or other mood disorders, Poxet 90 mg could potentially interact with medications you may be taking for these conditions. Ensure that your doctor is aware of your mental health history and any antidepressant or anti-anxiety medications you are using. Serotonin Syndrome Risk: There is a small risk of serotonin syndrome, a condition caused by excessive serotonin, if Poxet 90 mg is combined with certain other medications that affect serotonin (e.g., other SSRIs, SNRIs, or triptans). 4. Blood Pressure or Circulatory Issues Low Blood Pressure: If you have low blood pressure (hypotension), Poxet 90 mg may cause further lowering of blood pressure. If you experience symptoms like dizziness, lightheadedness, or fainting, seek medical help immediately. High Blood Pressure: While Poxet 90 mg does not directly affect blood pressure in the majority of cases, you should monitor your blood pressure regularly if you have high blood pressure, especially if you are on medication for hypertension. 5. Diabetes Effect on Blood Sugar: Although Poxet 90 mg is not directly associated with blood sugar changes, individuals with diabetes should monitor their condition closely when using any medication. Dapoxetine may potentially interact with other medications used to manage blood sugar levels. Drug Interactions: Always check with your doctor if you're on medications for diabetes as Poxet 90 mg can interact with some drugs that affect serotonin levels, which may indirectly influence glucose metabolism. 6. Alcohol and Substance Use Alcohol Use: Alcohol can enhance the sedative effects of Poxet 90 mg, causing dizziness, drowsiness, or a potential drop in blood pressure. It is advisable to avoid excessive alcohol consumption while taking this medication. Other Drugs: If you are taking other medications, especially for mental health disorders or heart conditions, discuss potential interactions with your doctor.