Cenforce products) for erectile dysfunction, and clinical guidelines recognize PDE-5 inhibitors such as sildenafil as a first-line treatment for ED in men with diabetes. P PubMed Central (PMC) +1 However, diabetes makes the overall cardiovascular and medication review particularly Cenforce : Diabetes itself can contribute to ED through blood-vessel and nerve damage. U Uroweb Do not use sildenafil with nitrate medicines such as nitroglycerin or isosorbide; the combination can cause a dangerous drop in blood pressure. D DailyMed Tell your doctor if you take alpha-blockers or blood-pressure medicines, because additional blood-pressure lowering can occur. D DailyMed Diabetes-related kidney or liver problems may affect the appropriate sildenafil dose. D DailyMed Don't combine Cenforce with another ED medicine such as Silditop, Fildena, Malegra, Filitra, or Tadarise.