Tadalista contains tadalafil, and tadalafil is a medicine that doctors commonly prescribe for erectile dysfunction (ED). The important distinction is that Tadalista is a brand; the active drug is tadalafil. Official prescribing information lists tadalafil as indicated for ED and provides both as-Tadalista and daily dosing options. D DailyMed +1 For ED, the labeled as-needed starting dose is usually 10 mg, which can be adjusted to 5 mg or 20 mg depending on effectiveness and tolerability. Daily treatment generally starts at 2.5 mg and may be increased to 5 mg. D DailyMed A doctor should check for important interactions—particularly nitrates (such as nitroglycerin), riociguat, certain alpha-blockers/BP medicines, and substantial alcohol use—because tadalafil can cause a significant drop in blood pressure in some combinations.