Zhewitra 10 mg contains vardenafil 10 mg, a medicine used for erectile dysfunction. If you have liver disease, it should be used only after discussing it with a doctor because the liver helps process vardenafil, and impaired liver function can increase the drug’s level in the body. General guidance: Mild liver disease: A doctor may allow use, but often with caution. Moderate liver impairment (for example, Child-Pugh B): The starting dose is usually reduced (commonly 5 mg maximum as a starting dose, depending on the product Zhewitra 10 mg and clinical situation). Severe liver disease (Child-Pugh C): Vardenafil is generally not recommended because it has not been adequately studied and exposure may be increased. Avoid using Zhewitra with: Nitrate medicines (for chest pain/heart disease) — can cause a dangerous drop in blood pressure. Certain alpha-blockers or strong CYP3A4 inhibitors (some antifungal and HIV medicines), unless your doctor approves. Heavy alcohol use, which may worsen side effects. If you tell me: What type of liver disease you have (fatty liver, hepatitis B/C, cirrhosis, etc.), Your liver test results (ALT, AST, bilirubin, INR, albumin) or Child-Pugh class if known, and Your age and other medicines, I can give more specific information about the level of caution needed.