Malegra DXT is a medication used to treat erectile dysfunction (ED), containing sildenafil citrate (the active ingredient in Viagra) and dapoxetine, which helps with premature ejaculation (PE). It works by increasing blood flow to the penis and delaying ejaculation. Why Malegra DXT May Not Work After Food: Effect of Fatty Meals on Absorption: Fatty or heavy meals can slow down the absorption of sildenafil (the main ingredient) in the body. Sildenafil is absorbed through the gastrointestinal tract, and if the stomach is full, Malegra DXT  after consuming a fatty meal, the drug can take longer to be absorbed, thus delaying its onset of action. This can make the medication less effective or slower to work when taken after a large meal. Dapoxetine and Food: Dapoxetine, which is used to treat premature ejaculation, may also be affected by food, though its effect is generally less influenced than sildenafil. However, consuming food might still slightly delay its absorption and reduce its overall effectiveness. Tips for Optimal Effectiveness of Malegra DXT: Take on an empty stomach: For the fastest and most effective results, it is recommended to take Malegra DXT 30-60 minutes before sexual activity, and ideally on an empty stomach or with a light meal. Avoid heavy or fatty meals: If you do eat, try to keep the meal light and low in fat to help the medication be absorbed more quickly.