Tadalista contains tadalafil, which is used to treat erectile dysfunction (ED) and sometimes benign prostatic hyperplasia (BPH). It works by improving blood flow to the penis, helping men achieve and maintain an erection when sexually aroused. Here's when you can take Tadalista safely: 1. When to Take Tadalista: Before Sexual Activity: For most men, Tadalista (typically 10 mg or 20 mg) is taken about 30 minutes to 1 hour before sexual activity. This gives the medication time to work, and its effects can last for up to 36 hours, allowing for spontaneous sexual activity without the need to plan ahead. Daily Use Option: If you are taking a low dose of Tadalista , like 2.5 mg or 5 mg, it can be taken daily, allowing you to engage in sexual activity whenever you desire, without needing to time the dose around specific sexual encounters. 2. With or Without Food: Tadalista can be taken with or without food. However, taking it with a large or fatty meal may delay the onset of the medication's action, as it could slow down the absorption process. So, if you want the medication to work faster, it's best to take it on an empty stomach or after a light meal. 3. Avoiding Alcohol and Grapefruit: It's generally recommended to limit alcohol consumption while using Tadalista, as it can increase the risk of side effects such as dizziness or low blood pressure. Grapefruit can interfere with how the medication works, so it’s best to avoid grapefruit or grapefruit juice when taking Tadalista. 4. Health Conditions to Consider: Heart Conditions: If you have any heart problems, especially those related to blood pressure, or if you are taking medications like nitrates for chest pain, you should avoid taking Tadalista or consult your doctor before use.