Vilitra (which contains vardenafil, a PDE5 inhibitor like sildenafil or tadalafil) does not usually increase blood pressure. In fact, it tends to have a mild blood pressure–lowering effect because it relaxes blood vessels to improve blood flow. Here’s the breakdown How Vilitra Affects Blood Pressure Mechanism: Vardenafil inhibits PDE5, increasing cGMP levels → smooth muscle relaxation → vasodilation. Result: Blood vessels widen, which can slightly lower blood pressure. Effect in Healthy Individuals: Minimal to moderate decrease in systolic/diastolic pressure (usually 5–10 mmHg). Most healthy men tolerate this without symptoms. Effect in People on Vilitra Pressure Medications: Combining Vilitra with nitrates or some alpha-blockers can cause dangerous drops in blood pressure. Dizziness, fainting, or even heart complications can occur. Not a Hypertensive Drug: Vilitra is not used to treat high blood pressure and does not raise it. Key Takeaways Vilitra generally lowers or slightly affects blood pressure, rather than increasing it. Avoid with nitrates or unstable cardiovascular conditions. Mild headaches or flushing are common due to vasodilation. If you want, I can make a quick comparison chart of Fildena, Cenforce, Vidalista, and Vilitra showing their blood pressure effects and main drug interactions — it’s really handy for safety purposes. Do you want me to do that?