Malegra 50 mg is a medication used to treat erectile dysfunction (ED) in men. It contains Sildenafil Citrate, the same active ingredient found in Viagra. Sildenafil works by improving blood flow to the penis, helping men with ED achieve and maintain an erection during sexual activity. How Malegra 50 mg Treats Erectile Dysfunction: Mechanism of Action: Sildenafil, the active ingredient in Malegra 50 mg, is a PDE5 inhibitor. In men with ED, the blood vessels in the penis do not relax enough, which limits blood flow and makes it difficult to achieve an erection. Sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic GMP (a substance that helps relax the smooth muscles in the penis). By blocking PDE5, Sildenafil increases cyclic GMP levels, promoting smooth muscle relaxation, and improving blood flow to the penis during sexual arousal, which helps the man achieve an erection. Dosage and Timing: Malegra 50 mg is usually taken 30 to 60 minutes before sexual activity. The effects typically last for 4 to 6 hours. It should not be taken more than once a day. Malegra 50 mg is often effective for men who require a moderate dose of Sildenafil. Side Effects: While Malegra 50 mg is generally safe for most men, some side effects may occur, including: Headaches Flushing Dizziness Upset stomach Nasal congestion In rare cases, more serious side effects such as priapism (prolonged erection), sudden vision or hearing loss, or chest pain can occur. Seek medical help if any of these side effects occur. Precautions: Do not take Malegra with nitrate medications (used for chest pain), as this can lead to a dangerous drop in blood pressure. Men with heart conditions, liver or kidney problems, or a history of stroke should consult their doctor before using Malegra 50 mg. Limit alcohol intake while using Malegra, as alcohol can increase the risk of side effects.