Kamagra, which contains sildenafil citrate, may interact with several medications, potentially leading to serious health risks. One major interaction is with nitrates, such as nitroglycerin or isosorbide, used for chest pain or heart conditions—this combination can cause a dangerous drop in blood pressure. Kamagra also interacts with alpha-blockers (e.g., doxazosin, tamsulosin) used for high blood pressure or enlarged prostate, which may lead to dizziness or fainting. Protease inhibitors used in HIV treatment (like ritonavir) can increase sildenafil levels in the blood, raising the risk of side effects. Other interacting drugs include certain antifungals (ketoconazole, itraconazole), antibiotics (erythromycin, clarithromycin), and medications affecting the CYP3A4 liver enzyme system. Additionally, combining Kamagra with recreational drugs like poppers (amyl nitrate) or excessive alcohol can be harmful. Always inform your doctor about all medications you are taking before using Kamagra to avoid dangerous interactions and ensure its safe use.