Vidalista contains tadalafil, a PDE-5 inhibitor used for erectile dysfunction. Some people should not take it, or should only take it after medical advice: Anyone taking nitrates such as nitroglycerin or isosorbide for chest pain. This combination can cause a dangerous drop in blood pressure. D DailyMed +1 Anyone taking riociguat or another guanylate-cyclase stimulator. D DailyMed Anyone with a serious allergy to tadalafil. D DailyMed People with certain serious heart or cardiovascular conditions, particularly when Vidalista activity itself has been advised against. D DailyMed People taking alpha-blockers or multiple blood-pressure medicines need medical guidance because blood pressure can fall too much. D DailyMed People with a previous episode of NAION (certain optic-nerve-related vision loss) should discuss tadalafil with a doctor before using it. D DailyMed You should not combine Vidalista with other ED medicines such as sildenafil/Cenforce or Fildena unless specifically instructed by a doctor. D DailyMed Important: If you develop sudden vision loss, sudden hearing loss, chest pain, or an erection lasting more than 4 hours after taking it, seek urgent medical care. D DailyMed If you tell me your age, Vidalista strength (10/20 mg), and any medicines you currently take, I can check for the major interaction risks.