Tadarise 60 mg is marketed as tadalafil, a PDE-5 inhibitor used to treat erectile dysfunction (ED). However, 60 mg is substantially above the usual maximum on-demand tadalafil dose of 20 mg for ED. Standard prescribing information recommends starting at 10 mg and adjusting to 20 mg or 5 mg depending on effectiveness and tolerability.

For men with heart disease-related ED, safety depends on the specific cardiac condition and its stability. PDE-5 inhibitors can be appropriate for some men with stable cardiovascular disease, but people with unstable angina, uncontrolled blood pressure, certain serious heart-failure conditions, recent heart attack or stroke, or high-risk arrhythmias may require cardiovascular evaluation before sexual activity or ED treatment.

The most important interaction is with nitrate medicines, including nitroglycerin and isosorbide. Tadalafil must not be used with nitrates because the combination can cause a potentially dangerous drop in blood pressure. Nitrates should generally be avoided for at least 48 hours after tadalafil.

Therefore, Tadarise 60 mg should not be self-used, particularly if you have cardiovascular disease. A cardiologist or other qualified clinician should determine whether tadalafil is appropriate and select a safer dose.

If chest pain, severe dizziness, fainting, or an erection lasting more than four hours occurs, seek emergency medical attention.