Fildena Double 200 mg should not be assumed safe with antibiotics. It is marketed as sildenafil 200 mg, but please verify the ingredients on your package. This is twice the usual maximum recommended sildenafil dose of 100 mg for erectile dysfunction, and it can increase the risk of side effects. Some antibiotics interact significantly with sildenafil: Erythromycin and clarithromycin: can increase sildenafil Fildena Double 200 mg in your blood. Rifampicin (rifampin): can reduce sildenafil levels and effectiveness. Other antibiotics: the risk depends on the specific medicine and your health. SILDENAFIL tablet, film coated +1 Tell me which antibiotic you take What is the exact name and dose of your antibiotic? For example, azithromycin 500 mg, amoxicillin 500 mg, or doxycycline 100 mg. Also, have you already taken Fildena Double 200 mg, or are you planning to take it? Until the interaction is checked, avoid taking the 200 mg tablet. If you develop sudden vision loss, chest pain, fainting, or an erection lasting over four hours, seek emergency medical care.