Malegra DXT Plus can cause flushing. This medicine typically contains Sildenafil Citrate (for erectile dysfunction) and Duloxetine (for premature ejaculation/anxiety-related control). The flushing effect is mainly due to sildenafil, which increases blood flow by relaxing blood vessels. What flushing feels like Warmth in the face, neck, or chest Redness of the skin A feeling of heat or mild discomfort Malegra DXT Plus it happens Sildenafil widens blood vessels (vasodilation), which can temporarily increase blood flow near the skin surface, causing flushing. This is a common and usually harmless side effect. When to be cautious Seek medical advice if flushing is: Severe or persistent Accompanied by chest pain, dizziness, or fainting Occurring along with allergic symptoms (rash, swelling, breathing trouble) In most cases, flushing is mild and short-lived, and it tends to reduce as your body adjusts or when taken with proper dosage and guidance.