The most common side effect of Vilitra, a medication used to treat erectile dysfunction, is headache. This occurs because Vilitra contains Vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor that works by relaxing the blood vessels in the penis to improve blood flow during sexual arousal. While this mechanism is effective for treating erectile dysfunction, it can also cause the blood vessels in other parts of the body, including the brain, to dilate, leading to mild to moderate headaches.

Headaches associated with Vilitra are usually temporary and tend to occur within a few hours of taking the medication. They are generally mild and resolve without the need for medical intervention, though over-the-counter pain relievers may be used if necessary. Other side effects can include dizziness, flushing, nasal congestion, and indigestion, but these are less common. Patients with a history of migraines or cardiovascular issues may be more prone to experiencing headaches after using Vilitra.

It is important to follow the prescribed dosage to minimize side effects and consult a doctor if headaches are severe or persistent.