If Tazzle 20 mg contains tadalafil 20 mg, alcohol is not absolutely prohibited, but heavy alcohol consumption should be avoided. Both tadalafil and alcohol can lower blood pressure. Drinking substantial amounts—around 5 or more alcohol units—with tadalafil can increase the risk of dizziness, Tazzle 20 mg , increased heart rate, and a drop in blood pressure when standing. For safer use: Avoid heavy drinking around the time you take tadalafil. Be especially cautious if you already have low blood pressure or take blood-pressure medicines or alpha-blockers. Never combine tadalafil with nitrate medicines such as nitroglycerin, because this can cause a dangerous fall in blood pressure. Also, 20 mg is the standard maximum as-needed tadalafil dose for ED, so it should be used according to medical advice.