liver injury from tadalafil appears to be rare. Most people do not develop liver damage from standard prescribed doses, although rare cases of liver inflammation have been reported. NCBI Bookshelf +1 The important concern is the 60 mg strength. If Tadalista 60 contains tadalafil  Tadalista 60  , that is above the usual maximum recommended on-demand dose of 20 mg for erectile dysfunction. Do not take another dose until you have consulted a clinician. People with liver disease may need lower doses, and tadalafil is not recommended in severe liver impairment. TADALAFIL tablet +1 Watch for warning signs of liver injury: Yellowing of the eyes or skin Dark urine or pale stools Persistent nausea or vomiting Pain in the upper-right abdomen Unusual itching or severe fatigue If these occur, seek prompt medical evaluation. Please tell me two things: Have you already taken Tadalista 60, or are you planning to take it? Do you have any existing liver problem or abnormal liver test results? These details will help me give you safer, more specific guidance.