Cenforce D Extra Power you mean the combination of sildenafil + dapoxetine, alcohol is best avoided because it can increase dizziness, low blood pressure, fainting, and impaired alertness. Dapoxetine in particular has a recognized risk of fainting that alcohol can worsen. H HealthHub +1 People who should especially avoid the combination Anyone taking nitrate medicines such as nitroglycerin or isosorbide for angina—sildenafil can cause a dangerous drop in blood pressure. A Apollo Pharmacy People with significant heart Cenforce D Extra Power or who have been advised that sexual activity is unsafe. A Apollo Pharmacy People with a history of fainting, particularly because dapoxetine can cause orthostatic dizziness/syncope. H HealthHub People taking MAO inhibitors or other serotonergic antidepressants without medical supervision, because of the risk of serious interactions with dapoxetine. G GNH India People taking other ED medicines such as tadalafil, vardenafil, or sildenafil-containing products, unless specifically instructed by a doctor. M MEDIONIX PHARMA If you've already taken Cenforce D Extra Power and alcohol, avoid driving and further alcohol. If you become very dizzy, faint, develop chest pain, or have an erection lasting more than 4 hours, seek urgent medical care.