Manforce 100 mg contains Sildenafil, the same active ingredient as Viagra, and is used to treat erectile dysfunction (ED) in men. An overdose of Sildenafil, including Manforce 100 mg, can be dangerous and increase the risk of severe side effects. Overdosing on this medication can be harmful to anyone, but certain groups may be more vulnerable to serious complications. Who is at risk when overdosing on Manforce 100 mg? People with Heart Conditions: Why: Sildenafil, including Manforce, can lower blood pressure, and if you have an existing heart condition (e.g., heart disease, low blood pressure, angina, or arrhythmias), this can be especially dangerous. Overdosing may cause further drops in blood pressure, leading to symptoms like dizziness, fainting, or even a heart attack or stroke in extreme cases. Recommendation: People with heart conditions Manforce 100 mg  use Sildenafil under strict medical supervision, and overdosing is very risky for them. People with Liver or Kidney Problems: Why: Both the liver and kidneys are responsible for breaking down and eliminating medications from your body. If you have liver or kidney disease, your body may not process Sildenafil properly, which could lead to an accumulation of the drug in your bloodstream and increase the risk of side effects such as dizziness, prolonged erections (priapism), or even heart problems. Recommendation: Individuals with liver or kidney issues should not take Manforce 100 mg without a doctor's guidance. An overdose in these cases can lead to severe complications. People with a History of Stroke: Why: Sildenafil can affect blood flow, and for people who have a history of stroke or brain disorders, overdosing may result in a further risk of stroke due to the potential changes in blood pressure and blood flow. Recommendation: Those with a history of stroke should consult a healthcare provider before using any Sildenafil-based medication like Manforce. Older Adults: Why: Older adults (especially those over 65 years of age) are often at increased risk when using medications like Sildenafil, especially if they are taking multiple medications for high blood pressure, diabetes, or other chronic conditions. Overdosing can increase the risk of side effects, including low blood pressure, heart problems, or dizziness. Recommendation: Older adults should use Sildenafil with caution and may require a lower dose. Overdosing can exacerbate the side effects.