Vilitra (which contains Vardenafil, a PDE5 inhibitor) is primarily prescribed for erectile dysfunction (ED). However, there are a few other situations where it might be used off-label or studied for potential benefits: 1. Primary Use – Erectile Dysfunction Vilitra increases blood flow to the penis during sexual arousal, helping men achieve and maintain an erection. It does not increase sexual desire; arousal is still required. 2. Off-Label / Investigational Uses Pulmonary Arterial Hypertension (PAH) Like other PDE5 inhibitors (sildenafil, tadalafil), vardenafil can relax blood vessels in the lungs, reducing pulmonary blood pressure. Vilitra use is off-label and requires careful medical supervision. Raynaud’s Phenomenon Rarely, PDE5 inhibitors are studied for improving blood flow in fingers and toes affected by Raynaud’s. Evidence is limited and it is not a standard treatment. Female Sexual Dysfunction (FSD) – Investigational Some small studies have looked at PDE5 inhibitors like vardenafil for enhancing genital blood flow in women, but results are mixed and it is not approved for this use. Diabetic or Vascular ED While technically still ED, Vilitra may be specifically prescribed for men whose erectile dysfunction is due to vascular problems, diabetes, or post-prostate surgery, because PDE5 inhibitors help with the blood flow issues underlying these conditions. Important Notes Vilitra is not approved for use in women or children. Any non-ED use should be supervised by a healthcare provider, as it can affect blood pressure and interact with other medications. If you want, I can make a side-by-side comparison of Vilitra vs Fildena vs Cenforce, showing approved uses, off-label uses, and differences in onset/duration. This helps see which drug might be chosen for which condition.