Filitra 40 mg is generally marketed as vardenafil 40 mg, a PDE-5 inhibitor for erectile dysfunction (ED). However, 40 mg is above the standard recommended maximum dose of vardenafil. For most adults, prescription vardenafil is started at 10 mg, with adjustment to 5–20 mg, and no more than one dose per day. D DailyMed +1 Who may use vardenafil? Adults with ED may be candidates, including some Filitra 40 mg  whose ED is associated with conditions such as diabetes, provided their cardiovascular health and other medicines make it appropriate. Filitra 40 mg specifically should not be self-used, because it exceeds the usual 20 mg maximum. Avoid vardenafil if you: Take nitrates such as nitroglycerin or isosorbide, or use “poppers.” Take riociguat. Have certain serious heart conditions where sexual activity itself is unsafe. Have congenital long-QT syndrome or take certain class IA/III antiarrhythmics. Have severe liver impairment or are on dialysis. D DailyMed +1 Also, don't combine it with sildenafil (Manforce, Suhagra, Penegra) or tadalafil (Tazzle, Tadacip, Tadarise, Tadfil) unless specifically instructed by a doctor. If you are considering Filitra 40 mg because 10 or 20 mg vardenafil hasn't worked, tell me that—I can explain safer options rather than increasing above the recommended dose.