Tadasoft 20 mg (which contains tadalafil, the same active ingredient as Cialis) can, in some people, be associated with mood‑related changes, such as anxiety, irritability, or low‑mood feelings, although this is not common. How it might affect mood Tadalafil mainly works on blood vessels and the penis, but it can also affect blood pressure and circulation in the brain, which may indirectly influence mood or anxiety in sensitive individuals. Some product information and clinical data mention “depression” or depressed mood as a reported, usually short‑lasting, effect during tadalafil use, though it is listed as a less‑common side effect. When to be cautious If you notice new or worsening mood swings, anxiety, or feelings of sadness after taking Tadasoft 20 mg, stop the medicine and consult a doctor promptly. People with a history of depression, bipolar disorder, or other psychiatric conditions should especially discuss tadalafil‑containing medicines with a physician before starting them. If you tell me your age, any current mental‑health issues, and what other medicines you take, I can help you understand risk factors more specifically (but this will not replace medical advice from your doctor or psychiatrist).