Tadalista (which contains tadalafil, another PDE5 inhibitor for erectile dysfunction) is 10 mg taken as needed, about 30 minutes before sexual activity. Some details: 5 mg – Sometimes prescribed for daily use if sexual activity is frequent (every day or almost every day). 10 mg – Most common Tadalista on-demand use. 20 mg – Higher on-demand dose for patients who don’t respond adequately to 10 mg. Tadalafil has a longer duration than other ED medications—effects can last up to 36 hours, which is why it’s sometimes called “the weekend pill.” If you want, I can make a quick comparison chart of Vilitra vs. Tadalista showing usual doses, onset, and duration—it makes the differences really clear.