Cenforce 100 mg is used for erectile dysfunction (ED) because it contains sildenafil 100 mg, a PDE-5 inhibitor. It works by: Increasing blood flow into the penis when you are sexually aroused. Helping the smooth muscle in penile blood vessels relax. Making it easier to get and maintain an erection. It doesn't automatically cause an erection and doesn't increase sexual desire. 100 mg is a relatively high sildenafil dose Cenforce 100 mg is generally the maximum recommended single dose. Many people start at 50 mg, with the dose adjusted according to effectiveness and side effects. It should not be taken more than once in 24 hours. Avoid sildenafil with nitrate medicines (such as nitroglycerin) because the combination can cause a dangerous drop in blood pressure. Also, don't combine Cenforce with other ED medicines such as Fildena, Malegra, Tadalista/Vidalista, or Vilitra/Filitra unless a doctor specifically tells you to.